Micro-SCY
Introducing micro-SCY™: a novel way of antibody-antigen interaction screening
micro-SCY™ is an innovative method for microarray-based characterization of antibody-antigen interactions, enabling systematic interaction screening in a highly biochemically relevant environment. The in-house by Future Diagnostics’ assay development experts. Future Diagnostics is currently offering micro-SCY™ as a service to IVD and biopharma companies, as well as antibody developers, producers and suppliers.
How does micro-SCY™ work?
micro-SCY™ screens antibody-antigen interactions in a microarray-based format in multiwell plates, offering a highly customizable and translatable setup for various antibody-based applications. A typical micro-SCY™ workflow consists of the following steps:
The benefits of using micro-SCY™ for antibody-antigen interaction screening
- Parallel & systematic assessment of antibodies and antibody pairs in small volumes (pL range), resulting in increased throughput.
- Highly translatable: Data is generated by an experimental setup highly relevant for immunoassays. This improves translatability compared to alternative technologies such as SPR and BLI.
- Customizable setup: Method can be adapted to accommodate desired specifications of our customers.
- Extensive and customizable output toolbox, including sensitivity, specificity, dynamic range, binding speed & strength, dissociation speed, matrix compatibility and lot-to-lot performance.
micro-SCY™ applications
- Screening capture or detection antibodies, antibody pairs and synergistic antibody mixes
- Raw material selection for biomarker assay development
- Cohort screen to identify antibodies that are clinically most relevant (specific isoform/conformation/modification)
- Clone selection in antibody development
- Lot-to-lot comparison and other antibody production optimizations
- Antibody performance vs. competitor products
More information?
Interested in using micro-SCY™ to characterize your antibodies? Contact our assay development experts to discuss your project needs!