Accusphere lyophilization

We make accuspheres to stabilize your biomolecules and enable ease of handling of your assay. The spheres can be used to reduce the assay turnaround time of any immunoassay or PCR reaction. Standard spheres have a size of 50μl (approximately 4.7 mm diameter) fit exactly in a single well of a microtiter plate. A successful example of an assay that makes use of the Accusphere Technique is the STAT Intra-Operative Intact PTH assay. This two-site chemiluminescent immunometric assay has only one pipetting step and an 8-minute turnaround time.

Accuphere balls
Bulk Accuspheres

Accuspheres are formed by combining a suitable matrix with the component of interest. This solution (minimal of 50 μl) is dripped into liquid nitrogen followed by a freeze-drying process, which forms the stable sphere.

Accusphere advantages:

  • Stabilization of your biomolecule
  • Reduction assay turnaround time (e.g. ELISA)
  • Ease of handling
  • Less incubation steps
  • Thermal protective characteristics

Biomolecules that can be used in accuspheres:

Antibodies
Proteins
Enzymes
Conjugates
PCR mixes glycerol-free
Oligonucleotides glycerol-free
Carbohydrates
Drug metabolites

Would you like to find out more about our accusphere services?

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